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Aminoshikimic acid
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Aminoshikimic acid : ウィキペディア英語版
Aminoshikimic acid

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Aminoshikimic acid is a synthetic crystalline carboxylic acid. It is characterized by multiple stereogenic centers and functional groups arrayed around a six-membered carbocyclic ring. Aminoshikimic acid is also an alternative to shikimic acid as a starting material for the synthesis of neuraminidase inhibitors such as the antiinfluenza agent oseltamivir (Tamiflu).
==History==
Aminoshikimic acid is an unnatural carbohydrate, although aminoshikimic acid is the namesake of the aminoshikimate pathway, which generates the 3-amino-5-hydroxybenzoic acid (AHBA) starter unit required for the biosynthesis of the ansamycins and mitomycins. The first microbe-catalyzed syntheses of aminoshikimic acid were described by Guo and Frost in 2004.

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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